Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20977206 | 0.94 | CA2 (0.47) | LTA4HEPHX2CA2CYP4A11FFAR1 | |
| SCHEMBL3474860 | 0.86 | CA2 (0.52) | CA2CYP4A11FFAR1CYP4F2TDP1 | |
| SCHEMBL5179689 | 0.81 | HDAC8 (0.43) | CA2FFAR1HDAC8 | |
| SCHEMBL239040 | 0.81 | CA2 (0.60) | LTA4HEPHX2CA2CYP4A11PPARA | |
| SCHEMBL81846 | 0.78 | TSHR (0.55) | LTA4HEPHX2CA2CYP4A11CYP11B1 | |
| SCHEMBL712627 | 0.78 | HSD17B10 (0.50) | CA2TSHRHSD17B10 | |
| SCHEMBL547631 | 0.78 | CA2 (0.58) | LTA4HEPHX2CA2CYP4A11PPARA | |
| SCHEMBL3069349 | 0.77 | HSD17B10 (0.37) | CA2FFAR1HDAC8TSHRHSD17B10 | |
| SCHEMBL31403397 | 0.77 | HSD17B10 (0.49) | CA2TSHRHSD17B10 | |
| SCHEMBL170113 | 0.77 | HSD17B10 (0.58) | CA2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975022-B1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018216822-A1 | NOVEL IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |
| EP-2975022-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014142298-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 富山化学工業株式会社 (JP) | 2014-09-18 | — | — | WO | disclosed |