SCHEMBL3474860

SCHEMBL3474860

C#Cc1ccc(CCO)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.52
TDP1 Q9NUW8 1/20 0.48
CA1 P00915 3/20 0.42
CA12 O43570 2/20 0.42
CA4 P22748 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX5 P09917 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
BACE1 P56817 1/20 0.41
FFAR1 O14842 2/20 0.41
ACACB O00763 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16070684 0.86 LTA4H (0.46) CA2TDP1TSHRFFAR1CYP4F2
SCHEMBL5179689 0.85 HDAC8 (0.43) CA2CA1CA12CA4CA9
SCHEMBL20977206 0.85 CA2 (0.47) CA2TSHRALDH1A1FFAR1CYP4F2
SCHEMBL516512 0.80 TSHR (0.43) CA2TDP1CA1CA12CA4
SCHEMBL40656 0.79 CA2 (0.77) CA2TDP1CA1CA12CA4
SCHEMBL16716398 0.78 ALDH1A1 (0.46) CA2CA1CA12CA4CA9
SCHEMBL22862360 0.78 CA2 (0.54) CA2TDP1CA1CA12CA4
SCHEMBL320278 0.76 LOXL2 (0.54) CA2TDP1CA12CA9CA14
SCHEMBL17662590 0.76 TAAR1 (0.50) CA2TDP1CA1CA12CA4
SCHEMBL670610 0.76 LPL (0.45) CA2TSHRACACBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235719-A1 DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2025-11-13 WO disclosed
US-20250136580-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-05-01 US disclosed
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed
US-20210317107-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2021-10-14 US disclosed
US-20210317107-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2021-10-14 US disclosed
US-20210149098-A1 OPTICAL ELEMENT, METHOD FOR FORMING PHOTO-ALIGNMENT PATTERN, AND METHOD FOR MANUFACTURING OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2021-05-20 US disclosed
US-10981896-B2 Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-04-20 US disclosed
US-10981896-B2 Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-04-20 US disclosed
US-20210002556-A1 COMPOUND, COMPOSITION, CURED OBJECT, OPTICALLY ANISOTROPIC BODY, AND REFLECTIVE FILM FUJIFILM CORPORATION (JP) 2021-01-07 US disclosed
EP-3192503-B1 NOVEL PHARMACEUTICAL COMPOSITION CONTAINING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF FUJIFILM TOYAMA CHEMICAL CO LTD (JP) 2019-08-14 EP disclosed
WO-2014142298-A1 NOVEL HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2014-09-18 WO disclosed
US-7781571-B2 Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light ALCON, INC. (CH) 2010-08-24 US disclosed
US-7781571-B2 Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light ALCON, INC. (CH) 2010-08-24 US disclosed
US-7781571-B2 Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light ALCON, INC. (CH) 2010-08-24 US disclosed
EP-2176242-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT Alcon, Inc. (CH) 2010-04-21 EP disclosed
WO-2009021097-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON, INC. (CH) 2009-02-12 WO disclosed
WO-2009021097-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON, INC. (CH) 2009-02-12 WO disclosed
US-20090043105-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON, INC. (CH) 2009-02-12 US disclosed
US-20090043105-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON, INC. (CH) 2009-02-12 US disclosed
US-20090043105-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT ALCON, INC. (CH) 2009-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043105-A1 OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT CRYAB, CRYAA, UACA CA2 1364/4885TDP1 2246/4885CA1 1778/4885
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT SP1, C5, ZYX CA2 1198/4885TDP1 4427/4885CA1 132/4885
US-20210317107-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE MELK, HIPK1, HIPK3 CA2 4524/4885TDP1 2053/4885CA1 4078/4885
US-10981896-B2 Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase MELK, HIPK1, HIPK3 CA2 4553/4885TDP1 2175/4885CA1 4119/4885
US-20210002556-A1 COMPOUND, COMPOSITION, CURED OBJECT, OPTICALLY ANISOTROPIC BODY, AND REFLECTIVE FILM MKI67, RB1, FLNA CA2 3391/4885TDP1 4194/4885CA1 1075/4885
US-20250136580-A1 INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE MELK, HIPK1, HIPK3 CA2 4524/4885TDP1 2053/4885CA1 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.