SCHEMBL16070720

SCHEMBL16070720

CCO[C@@H](C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
CYP3A4 P08684 3/20 0.62
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
RAB9A P51151 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 3/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
HSD17B10 Q99714 1/20 0.46
PGR P06401 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
HTR2A P28223 1/20 0.46
HRH1 P35367 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5446932 1.00 ALDH1A1 (0.62) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL36134 1.00 ALDH1A1 (0.62) ALDH1A1CYP3A4MEN1KMT2ANPC1
Propane SCHEMBL28250363 0.98 ALDH1A1 (0.60) ALDH1A1CYP3A4MEN1KMT2ANPC1
Water SCHEMBL23175322 0.98 ALDH1A1 (0.60) ALDH1A1CYP3A4MEN1KMT2ANPC1
Benzil SCHEMBL1618410 0.95 ALDH1A1 (0.57) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL3663673 0.94 ALDH1A1 (0.55) ALDH1A1CYP3A4MEN1KMT2ANPC1
Benzoin SCHEMBL16649154 0.92 LMNA (0.64) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL8067333 0.91 ALDH1A1 (0.53) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL28247486 0.91 ALDH1A1 (0.53) ALDH1A1CYP3A4MEN1KMT2ANPC1
Benzylamine SCHEMBL28120524 0.89 ALDH1A1 (0.51) ALDH1A1CYP3A4MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200231872-A1 PHOSPHOR AND A COMPOSITION MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
EP-2418536-B1 LIQUID CRYSTAL DISPLAY DEVICE and COMPOSITION FOR FORMING a POLYMER LAYER SHARP KK (JP) 2014-09-17 EP disclosed