Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FURIN | P09958 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30433664 | 0.82 | HPGD (0.56) | MAPTALDH1A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL20543330 | 0.82 | MAPT (0.72) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL15630167 | 0.80 | SMN1; SMN2 (0.49) | MAPTALDH1A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL12514955 | 0.79 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL12018032 | 0.78 | RAB9A (0.46) | MAPTALDH1A1SMN1; SMN2NPC1GAA | |
| SCHEMBL13753209 | 0.77 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2NPC1THRB | |
| SCHEMBL21731488 | 0.77 | HPGD (0.72) | MAPTALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL12211157 | 0.76 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2NPC1FURIN | |
| SCHEMBL27892102 | 0.76 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL7566026 | 0.76 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014141094-A1 | ANTICANCER CONJUGATE | ADAMED SP. Z O.O. (PL) | 2014-09-18 | — | — | WO | disclosed |