SCHEMBL16076532

SCHEMBL16076532

CCC(C)COCCC[Si](O)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR6 P43657 3/20 0.32
LPAR1 Q92633 3/20 0.32
LPAR4 Q99677 3/20 0.32
LPAR5 Q9H1C0 3/20 0.32
LPAR2 Q9HBW0 3/20 0.32
LPAR3 Q9UBY5 3/20 0.32
HSD17B10 Q99714 1/20 0.31
SPHK1 Q9NYA1 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16076537 0.83
SCHEMBL2759261 0.81 LMNA (0.34) LPAR6LPAR1LPAR4LPAR5LPAR2
SCHEMBL16076538 0.81
SCHEMBL14369618 0.81 LPAR1 (0.41) LPAR6LPAR1LPAR4LPAR5LPAR2
SCHEMBL16076531 0.80
SCHEMBL25638703 0.75 USP2 (0.53) LPAR5HSD17B10USP2
SCHEMBL29309498 0.75 TSHR (0.38) HSD17B10USP2
SCHEMBL17126850 0.74 USP2 (0.43) LPAR6LPAR1LPAR4LPAR5LPAR2
SCHEMBL2759265 0.73 HSD17B10 (0.31) HSD17B10
SCHEMBL2759262 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9329158-B2 Epoxy chemistry derived materials as mixed mode chromatography media, method for their synthesis and use DIONEX CORPORATION (US) 2016-05-03 US disclosed
US-20140273264-A1 EPOXY CHEMISTRY DERIVED MATERIALS AS MIXED MODE CHROMATOGRAPHY MEDIA, METHOD FOR THEIR SYNTHESIS AND USE DIONEX CORPORATION 2014-09-18 US disclosed