SCHEMBL25638703

SCHEMBL25638703

CO[Si](O)(CCCOCC(O)CO)OC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.53
HTT P42858 1/20 0.36
LMNA P02545 2/20 0.34
AGTR1 P30556 1/20 0.34
CYP1A2 P05177 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
LPAR5 Q9H1C0 1/20 0.32
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1106391 0.84 USP2 (0.51) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL428119 0.84 USP2 (0.55) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL430465 0.84 USP2 (0.55) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL14089863 0.82 USP2 (0.53) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL16588236 0.82 USP2 (0.53) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL13044735 0.81 USP2 (0.56) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL14962633 0.81 USP2 (0.56) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL5854880 0.81 USP2 (0.55) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL373637 0.79 USP2 (0.58) USP2HTTLMNAAGTR1CYP1A2
SCHEMBL31026687 0.79 USP2 (0.54) USP2HTTLMNAAGTR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230182114-A1 DOUBLE SURFACE MODIFIED POROUS MATERIAL WITH MINIMIZED NONSPECIFIC INTERACTION WATERS TECHNOLOGIES CORPORATION (US) 2023-06-15 US disclosed