Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.45 |
| ▸ | PYGL | P06737 | 3/20 | 0.41 |
| ▸ | PYGM | P11217 | 2/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812551 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMSLC5A2SLC5A1 | |
| SCHEMBL23816577 | 0.82 | PYGB (0.44) | PYGBPYGLPYGMSLC5A2SLC5A1 | |
| SCHEMBL13329653 | 0.80 | PYGB (0.35) | PYGBPYGLPYGMSLC5A2SLC5A1 | |
| SCHEMBL16076764 | 0.79 | PYGB (0.42) | PYGBPYGLPYGMSLC5A2SLC5A1 | |
| SCHEMBL12928886 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM | |
| SCHEMBL17035712 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM | |
| SCHEMBL16638842 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM | |
| SCHEMBL17035715 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM | |
| SCHEMBL17035722 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM | |
| SCHEMBL12899848 | 0.79 | PYGB (0.40) | PYGBPYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890176-B2 | Mannose derivatives for treating bacterial infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-02-13 | — | — | US | disclosed |
| US-20140274930-A1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274930-A1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | TLR5, TLR1, MANBA | PYGB 3833/4885PYGL 1551/4885PYGM 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.