Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963181 | 0.83 | CNR1 (0.50) | POLBKMT2ANPC1 | |
| SCHEMBL16073055 | 0.82 | GAA (0.53) | GAAHTTALOX15P2RX7POLB | |
| SCHEMBL16073081 | 0.78 | HTT (0.52) | GAAHTTALOX15P2RX7KMT2A | |
| SCHEMBL16078328 | 0.78 | GAA (0.49) | GAAHTTALOX15P2RX7POLB | |
| SCHEMBL12858259 | 0.76 | GAA (0.54) | GAAHTTALOX15P2RX7POLB | |
| SCHEMBL18671008 | 0.71 | CNR2 (0.52) | GAAHTTALOX15P2RX7POLB | |
| SCHEMBL30944393 | 0.71 | CNR1 (0.71) | GAAHTTALOX15KMT2ANPC1 | |
| SCHEMBL2690664 | 0.71 | FFAR2 (0.53) | FFAR2 | |
| SCHEMBL16073067 | 0.71 | CNR2 (0.51) | GAAHTTALOX15P2RX7POLB | |
| SCHEMBL30944404 | 0.70 | NPC1 (0.56) | GAAHTTALOX15P2RX7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604946-B2 | Methods for modulating bacterial virulence and related compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-28 | — | — | US | disclosed |
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275189-A1 | Methods for Modulating Bacterial Virulence and Related Compounds | STAT1, MLEC, CGAS | GAA 3218/4885HTT 4567/4885ALOX15 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.