Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944281 | 0.84 | NPC1 (0.55) | NPC1KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL28521684 | 0.84 | NPC1 (0.55) | NPC1KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL28530631 | 0.82 | DYRK1A (0.55) | NPC1KMT2ARAB9AMEN1HTT | |
| SCHEMBL30944384 | 0.82 | DYRK1A (0.55) | NPC1KMT2ARAB9AMEN1HTT | |
| SCHEMBL30944315 | 0.82 | P2RX7 (0.47) | NPC1KMT2ARAB9AGAAHTT | |
| SCHEMBL30944410 | 0.82 | GAA (0.47) | NPC1KMT2ARAB9AGAAHTT | |
| SCHEMBL30944369 | 0.80 | GAA (0.44) | NPC1KMT2ARAB9AMEN1GAA | |
| SCHEMBL30944407 | 0.78 | NPC1 (0.50) | NPC1KMT2ARAB9AMEN1GAA | |
| SCHEMBL30944393 | 0.78 | CNR1 (0.71) | NPC1KMT2ARAB9AMEN1GAA | |
| SCHEMBL30944382 | 0.77 | CNR1 (0.49) | NPC1KMT2ARAB9AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |