Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065006 | 0.93 | PREP (0.34) | PREPHTRA1ELANEALDH1A1 | |
| SCHEMBL18828792 | 0.91 | HTRA1 (0.33) | PREPHTRA1 | |
| SCHEMBL16065007 | 0.85 | CTSC (0.42) | PREP | |
| SCHEMBL15081660 | 0.85 | PREP (0.44) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL18828790 | 0.85 | PREP (0.41) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL18643728 | 0.82 | PREP (0.42) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL22642842 | 0.82 | PREP (0.40) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL16078799 | 0.82 | PREP (0.40) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL16064115 | 0.82 | PREP (0.42) | PREPHTRA1CHRM2CHRM1CHRM3 | |
| SCHEMBL15064894 | 0.81 | PREP (0.44) | PREPHTRA1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871783-B2 | Substituted 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid (cyano-methyl)-amides inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-28 | — | — | US | disclosed |
| US-20140275114-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275114-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | CTSC, CTSB, CTSV | PREP 39/4885HTRA1 721/4885CHRM2 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.