Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19592300 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL19200397 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL18733077 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL12257878 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL15966293 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL26491587 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL15966302 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL16887713 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL19038904 | 0.87 | — | — | |
| SCHEMBL23902618 | 0.85 | TDP1 (0.31) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
| US-9428479-B2 | Conversion of biomass | XYLECO, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-9063445-B2 | Toner for electrostatic image development, production method of the toner and image formation method | Konica Minolta, Inc. (JP) | 2015-06-23 | — | — | US | disclosed |
| US-20140272694-A1 | TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT, PRODUCTION METHOD OF THE TONER AND IMAGE FORMATION METHOD | Konica Minolta, Inc. (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140011248-A1 | CONVERSION OF BIOMASS | XYLECO, INC. | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011248-A1 | CONVERSION OF BIOMASS | PFKFB2, PFKFB3, PFKFB1 | TDP1 2245/4885LMNA 3722/4885L3MBTL1 2205/4885 |
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | EPX, DNASE1, DERA | TDP1 158/4885LMNA 1560/4885L3MBTL1 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.