Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430124 | 0.87 | NOTUM (0.64) | NOTUMMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6605105 | 0.84 | NOTUM (0.64) | NOTUMMAPTKMT2AKDM4EMEN1 | |
| Quinoline SCHEMBL27846212 | 0.83 | NOTUM (0.52) | NOTUMHSD17B3ALDH1A1CNR2 | |
| SCHEMBL6607583 | 0.83 | NOTUM (0.62) | NOTUMMAPTLMNAALDH1A1CNR2 | |
| SCHEMBL3025336 | 0.83 | NOTUM (0.62) | NOTUMHSD17B3CNR2AMPD2 | |
| SCHEMBL5461555 | 0.83 | NOTUM (0.62) | NOTUMMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6527995 | 0.83 | NOTUM (0.62) | NOTUMMAPTKMT2AKDM4EHSD17B3 | |
| SCHEMBL2204666 | 0.80 | NOTUM (0.59) | NOTUMMAPTKDM4EHSD17B3LMNA | |
| SCHEMBL1654554 | 0.79 | NOTUM (0.57) | NOTUMMAPTKDM4EHTTLMNA | |
| SCHEMBL6606078 | 0.79 | NOTUM (0.57) | NOTUMKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924395-A1 | B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-21 | — | — | US | disclosed |
| CN-113423742-A | Bis (arylphenolate) lewis base catalysts and processes thereof | 埃克森美孚化学专利公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020167824-A1 | B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020167824-A1 | B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| US-20200254431-A1 | BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-08-13 | — | — | US | disclosed |
| US-20200254431-A1 | BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-08-13 | — | — | US | disclosed |
| US-20110080458-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, INC. | 2011-04-07 | — | — | US | disclosed |
| US-7704667-B2 | Dyes and use thereof in imaging members and methods | ZINK IMAGING, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| WO-2009097433-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20080187866-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | PHKB, TYR, ELL | NOTUM 1573/4885MAPT 2984/4885KMT2A 1420/4885 |
| US-20080187866-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | CACYBP, KLHDC2, ZKSCAN2 | NOTUM 1290/4885MAPT 423/4885KMT2A 4563/4885 |
| US-20110080458-A1 | NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | CACYBP, KLHDC2, ZKSCAN2 | NOTUM 1290/4885MAPT 423/4885KMT2A 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.