Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27975048 | 0.87 | NOTUM (0.70) | NOTUMALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL430124 | 0.72 | NOTUM (0.64) | NOTUMALDH1A1HSD17B3HTR3EHTR3B | |
| SCHEMBL447187 | 0.70 | NOTUM (1.00) | NOTUMALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL6605105 | 0.70 | NOTUM (0.64) | NOTUMALDH1A1HSD17B3CNR2 | |
| SCHEMBL6527995 | 0.69 | NOTUM (0.62) | NOTUMALDH1A1HSD17B3CNR2 | |
| SCHEMBL3025336 | 0.69 | NOTUM (0.62) | NOTUMHSD17B3CNR2 | |
| SCHEMBL6607583 | 0.69 | NOTUM (0.62) | NOTUMALDH1A1NPC1RAB9ACNR2 | |
| Quinoline SCHEMBL27635795 | 0.68 | ALDH1A1 (0.74) | ALDH1A1NPC1POLBRAB9A | |
| Quinoline SCHEMBL28166319 | 0.67 | ALDH1A1 (0.89) | ALDH1A1NPC1POLBRAB9A | |
| Quinoline SCHEMBL1783847 | 0.67 | ALDH1A1 (0.71) | ALDH1A1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203066-A | Novel dyes and use thereof in imaging members and methods | ZINK IMAGING INC | 2011-09-28 | — | — | CN | disclosed |