SCHEMBL16079774

SCHEMBL16079774

CC(C)NCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCNC(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
ADRB2 P07550 1/20 0.31
HTR1B P28222 1/20 0.30
NR2E1 Q9Y466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16084539 0.78
SCHEMBL26084658 0.76 KDM4E (0.31)
SCHEMBL26770215 0.76 EPHX1 (0.33)
SCHEMBL11807873 0.75 HRH4 (0.32) HRH4HRH3ADRB2HTR1BNR2E1
SCHEMBL2866747 0.75
SCHEMBL14848714 0.74 EPHX1 (0.32)
SCHEMBL8621578 0.72 HRH4 (0.33) HRH4HRH3ADRB2HTR1BNR2E1
SCHEMBL15981492 0.71 HRH4 (0.34) HRH4HRH3ADRB2
SCHEMBL432341 0.71 CA12 (0.44)
SCHEMBL29169937 0.71 EPHX1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170135911-A1 CURABLE COMPOSITIONS AND METHODS FOR ISOLATING A WORKING AREA SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2017-05-18 US disclosed
US-9139753-B2 Single-component moisture-curable coatings based on N-substituted urea polymers with extended chains and terminal alkoxysilanes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-22 US disclosed
US-20140275405-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170135911-A1 CURABLE COMPOSITIONS AND METHODS FOR ISOLATING A WORKING AREA BCCIP, EPM2A, EMD HRH4 3600/4885HRH3 2035/4885ADRB2 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.