SCHEMBL432341

SCHEMBL432341

C[Si](C)(CCCNCCN)O[Si](C)(C)O[Si](C)(C)CCCNCCN

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.44
CA6 P23280 5/20 0.44
CA7 P43166 5/20 0.44
CA9 Q16790 5/20 0.44
CA14 Q9ULX7 5/20 0.44
CA5B Q9Y2D0 5/20 0.44
CA2 P00918 4/20 0.44
CA4 P22748 4/20 0.44
CA5A P35218 4/20 0.44
CA3 P07451 3/20 0.44
MEN1 O00255 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALOX15 P16050 3/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19286516 0.93 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL13056510 0.93 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL2866750 0.91 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL13609007 0.90 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL12191358 0.89 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL12191368 0.89 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL19764098 0.89 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL12191371 0.88 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL30313518 0.85 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL30925269 0.85 CA12 (0.50) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295433-A1 SILICONE EMULSION COMPOSITION AND FIBER TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-21 US disclosed
EP-4198091-A1 SILICONE EMULSION COMPOSITION AND FIBER TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-21 EP disclosed
US-9180321-B2 Cosmetic compositions containing liposoluble polymers and tackifiers L'OREAL S.A. (FR) 2015-11-10 US disclosed
US-9017648-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and a particular additional ingredient L'OREAL (FR) 2015-04-28 US disclosed
US-8980240-B2 Eyelash makeup and/or care assembly L'OREAL (FR) 2015-03-17 US disclosed
US-8728500-B2 Composition containing a polyorganosiloxane polymer, a thickening agent and at least one volatile alcohol L'OREAL (FR) 2014-05-20 US disclosed
US-20130004438-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT L'OREAL (FR) 2013-01-03 US disclosed
US-20120301415-A1 COMPOSITIONS HAVING ENHANCED COSMETIC PROPERTIES L'OREAL (FR) 2012-11-29 US disclosed
US-8313735-B2 Long-wearing cosmetic product system for providing extended shine and gloss L'OREAL (FR) 2012-11-20 US disclosed
US-8241617-B2 Methods for removing make-up compositions from keratin materials L'ORÉAL (FR) 2012-08-14 US disclosed
US-20080102048-A1 Long-wearing cosmetic product system for providing extended shine and gloss L'OREAL (FR) 2008-05-01 US disclosed
US-20080102049-A1 Long-wearing cosmetic product system having high shine and gloss L'OREAL (FR) 2008-05-01 US disclosed
US-20080044373-A1 Cosmetic composition for the lips, combining a phosphate surfactant and a silicone polymer L'OREAL (FR) 2008-02-21 US disclosed
US-7329699-B2 Composition containing oil, structuring polymer, and coated silicone elastomer, and methods of making and using the same L'OREAL (FR) 2008-02-12 US disclosed
US-7321011-B2 Self-emulsifying copolymer L'OREAL (FR) 2008-01-22 US disclosed
US-20070231287-A1 COSMETIC COMPOSITION FOR CARE AND/OR TREATMENT AND/OR MAKEUP OF THE EMULSION TYPE STRUCTURED WITH SILICONE POLYMERS L'OREAL (FR) 2007-10-04 US disclosed
US-20070093619-A1 Compositions having enhanced cosmetic properties L'OREAL (FR) 2007-04-26 US disclosed
US-20070053859-A1 Compostions containing silicone polymer, wax and volatile solvent L'OREAL (FR) 2007-03-08 US disclosed
US-20070055014-A1 Cosmetic compositions containing block copolymers, tackifiers and phenylated silicones L'OREAL (FR) 2007-03-08 US disclosed
US-20070041928-A1 Methods for removing make-up compositions from keratin materials L'OREAL (FR) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080102048-A1 Long-wearing cosmetic product system for providing extended shine and gloss CUTA, KRT18, KRTCAP2 CA12 111/4885CA6 1414/4885CA7 2007/4885
US-20080044373-A1 Cosmetic composition for the lips, combining a phosphate surfactant and a silicone polymer PTEN, PHOSPHO1, LIPA CA12 1448/4885CA6 1750/4885CA7 510/4885
US-20070041928-A1 Methods for removing make-up compositions from keratin materials KRT18, CUTA, SMURF1 CA12 2335/4885CA6 2637/4885CA7 1050/4885
US-20130004438-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT FDFT1, ESD, SCO2 CA12 2357/4885CA6 3150/4885CA7 1628/4885
US-20070053859-A1 Compostions containing silicone polymer, wax and volatile solvent PUF60, SQLE, TAF5 CA12 1058/4885CA6 2918/4885CA7 404/4885
US-20120301415-A1 COMPOSITIONS HAVING ENHANCED COSMETIC PROPERTIES RARA, CUTA, RXRA CA12 3919/4885CA6 3491/4885CA7 1984/4885
US-20080102049-A1 Long-wearing cosmetic product system having high shine and gloss CUTA, TST, TGM3 CA12 349/4885CA6 1020/4885CA7 1035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.