Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.45 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101981 | 0.85 | ALDH1A1 (0.37) | GRIN2BPGRGCGRMAPK1HTR2A | |
| SCHEMBL9008497 | 0.85 | PGR (0.33) | CYP3A4KDM1AGRIN2BPGRMAOB | |
| SCHEMBL18458568 | 0.85 | HTR2C (0.41) | KDM1AGRIN2BPGRMAOBHTR2A | |
| SCHEMBL8101984 | 0.85 | ALDH1A1 (0.37) | GRIN2BPGRGCGRMAPK1HTR2A | |
| SCHEMBL9008501 | 0.85 | PGR (0.33) | CYP3A4KDM1AGRIN2BPGRMAOB | |
| SCHEMBL28710455 | 0.84 | ESR2 (0.58) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL7936157 | 0.83 | CYP2C9 (0.42) | ESR2CYP2C9PGRGCGRMAPK1 | |
| SCHEMBL7936155 | 0.83 | CYP2C9 (0.42) | ESR2CYP2C9PGRGCGRMAPK1 | |
| SCHEMBL18800297 | 0.82 | HTR2A (0.38) | KDM1AGRIN2BPGRHTR2AHTR2C | |
| SCHEMBL16258085 | 0.82 | ALDH1A1 (0.35) | GRIN2BPGRGCGRMAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | PIK3CD, TEC, PIK3C3 | ESR2 2052/4885ESR1 1750/4885CYP3A4 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.