SCHEMBL1608154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13935179	0.93	COMT (0.39)	APPCOMTNPC1KDM4ERAB9A
	SCHEMBL1609346	0.88	COMT (0.43)	APPCOMTNPC1KDM4ERAB9A
	SCHEMBL3815204	0.81	CDC7 (0.33)	APPCOMTNPC1KDM4ERAB9A
	SCHEMBL13935177	0.81	CCNE1 (0.34)	APPNPC1KDM4ERAB9ACDC7
	SCHEMBL1608166	0.75	MAPT (0.45)	COMTRAB9A
	SCHEMBL8054509	0.68	APP (0.63)	APPNPC1KDM4ERAB9ACDC7
	SCHEMBL13935093	0.68	APP (0.43)	APPCOMTNPC1KDM4ERAB9A
	SCHEMBL19757223	0.62	APP (0.52)	APPKDM4ERAB9AMMP2MMP9
	SCHEMBL25026544	0.62	KDM4E (0.67)	APPNPC1KDM4ERAB9A
	SCHEMBL11371956	0.61	GPR35 (0.51)	NPC1KDM4ERAB9ACDC7PKN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.