SCHEMBL1609346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1608154	0.88	APP (0.39)	COMTAPPMMP2MMP9MMP8
	SCHEMBL13935179	0.82	COMT (0.39)	COMTAPPALDH1A1KDM4ESMN1; SMN2
	SCHEMBL13935093	0.79	APP (0.43)	COMTAPPMMP2MMP9MMP8
	SCHEMBL1608166	0.76	MAPT (0.45)	COMTALDH1A1SMN1; SMN2HPGDMAPT
	SCHEMBL27944835	0.71	MEN1 (0.55)	APPMMP2MMP9MMP8MMP13
	SCHEMBL3815204	0.70	CDC7 (0.33)	COMTAPPMMP2MMP9MMP8
	SCHEMBL2141665	0.70	APP (0.69)	APPMMP2MMP9MMP8MMP13
	SCHEMBL15818306	0.68	APP (0.51)	APPMMP2MMP9MMP8MMP13
	SCHEMBL2136576	0.67	APP (0.69)	APPMMP2MMP9MMP8MMP13
	SCHEMBL1609375	0.65	GPR35 (0.46)	COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.