Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081528 | 0.98 | CALM1 (0.42) | CALM1CAMKK2TSHRABCB1MAPK1 | |
| SCHEMBL12918861 | 0.91 | TSHR (0.45) | CALM1CAMKK2TSHRABCB1GAA | |
| SCHEMBL10126562 | 0.82 | HTT (0.47) | TSHRABCB1HDAC3HDAC1HDAC2 | |
| SCHEMBL22498765 | 0.82 | CARM1 (0.46) | CALM1CAMKK2TSHRABCB1SMN1; SMN2 | |
| SCHEMBL18073542 | 0.82 | CALM1 (0.44) | CALM1CAMKK2TSHRABCB1MAPK1 | |
| SCHEMBL10138451 | 0.82 | TSHR (0.47) | CALM1CAMKK2TSHRMAPK1GAA | |
| SCHEMBL7692544 | 0.82 | HTT (0.47) | TSHRABCB1HDAC3HDAC1HDAC2 | |
| SCHEMBL15357270 | 0.82 | CALM1 (0.44) | CALM1CAMKK2TSHRABCB1MAPK1 | |
| SCHEMBL29467599 | 0.82 | CALM1 (0.44) | CALM1CAMKK2TSHRABCB1MAPK1 | |
| SCHEMBL14870667 | 0.82 | TSHR (0.47) | CALM1CAMKK2TSHRMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144017-A2 | COMPOSITIONS AND METHODS FOR TREATING CONDITIONS THAT AFFECT EPIDERMIS | GENCIA CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |