Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18929628 | 1.00 | PAOX (0.44) | PAOXLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL8258492 | 1.00 | PAOX (0.44) | PAOXLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL22064891 | 0.98 | — | — | |
| SCHEMBL14466067 | 0.90 | — | — | |
| SCHEMBL16003068 | 0.87 | ALDH1A1 (0.38) | LMNAALDH1A1RECQLTSHR | |
| SCHEMBL10878257 | 0.80 | LMNA (0.44) | PAOXLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL2370162 | 0.80 | LMNA (0.44) | PAOXLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9831499 | 0.80 | LMNA (0.44) | PAOXLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL14160325 | 0.79 | — | — | |
| SCHEMBL1453654 | 0.78 | ALDH1A1 (0.33) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014145035-A1 | METHODS OF MAKING CANCER COMPOSITIONS | GENSPERA, INC. (US) | 2014-09-18 | — | — | WO | disclosed |