Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 2/20 | 0.47 |
| ▸ | ATP4B | P51164 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22594687 | 0.84 | RAB9A (0.62) | RAB9AMAPTALDH1A1ALOX5GRM1 | |
| SCHEMBL12070478 | 0.82 | RAB9A (0.60) | RAB9AMAPTALDH1A1GRM1NPC1 | |
| SCHEMBL7476639 | 0.82 | RAB9A (0.60) | RAB9AMAPTALDH1A1ALOX5NPC1 | |
| SCHEMBL1009194 | 0.82 | RAB9A (0.68) | RAB9AMAPTALDH1A1ALOX5GRM1 | |
| SCHEMBL9481963 | 0.81 | RAB9A (0.62) | RAB9AMAPTALDH1A1GRM1NPC1 | |
| SCHEMBL6406776 | 0.78 | RAB9A (0.60) | RAB9AMAPTALDH1A1GRM1NPC1 | |
| SCHEMBL6406779 | 0.78 | RAB9A (0.60) | RAB9AMAPTALDH1A1GRM1NPC1 | |
| SCHEMBL1474111 | 0.77 | RAB9A (0.63) | RAB9AMAPTALDH1A1GRM1NPC1 | |
| SCHEMBL23486602 | 0.76 | RAB9A (0.54) | RAB9AMAPTALDH1A1NPC1MEN1 | |
| SCHEMBL7472306 | 0.76 | MAPT (1.00) | RAB9AMAPTALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139882-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2014-09-18 | — | — | WO | disclosed |