Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486303 | 0.85 | RAB9A (0.51) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| SCHEMBL23460184 | 0.83 | RAB9A (0.49) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| Hydrochloric Acid SCHEMBL23460152 | 0.82 | RAB9A (0.48) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| SCHEMBL23486301 | 0.80 | RAB9A (0.46) | RAB9AMAPTLTA4HNPC1KMT2A | |
| SCHEMBL3440378 | 0.80 | PRMT6 (0.68) | RAB9AMAPTPRMT6ADRB2LTA4H | |
| SCHEMBL22594687 | 0.77 | RAB9A (0.62) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| SCHEMBL16083113 | 0.76 | RAB9A (0.60) | RAB9AMAPTNPC1PTGS2KMT2A | |
| SCHEMBL12070478 | 0.76 | RAB9A (0.60) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| SCHEMBL7476639 | 0.76 | RAB9A (0.60) | RAB9AMAPTLTA4HNPC1PTGS2 | |
| SCHEMBL1009194 | 0.76 | RAB9A (0.68) | RAB9AMAPTLTA4HNPC1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113263-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-06-10 | — | — | WO | disclosed |