Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 16/20 | 0.59 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049579 | 0.81 | PKLR (0.77) | PKLR | |
| SCHEMBL21976495 | 0.77 | PKLR (0.70) | PKLR | |
| SCHEMBL21976864 | 0.77 | PKLR (0.70) | PKLR | |
| SCHEMBL21975989 | 0.76 | PKLR (0.66) | PKLRCYP46A1 | |
| SCHEMBL21976449 | 0.76 | PKLR (0.70) | PKLR | |
| SCHEMBL21976414 | 0.75 | PKLR (0.52) | PKLR | |
| SCHEMBL17320173 | 0.75 | PKLR (0.67) | PKLR | |
| SCHEMBL21976741 | 0.75 | PKLR (0.70) | PKLR | |
| SCHEMBL21976822 | 0.75 | PKLR (0.60) | PKLRAVPR1ACYP46A1 | |
| SCHEMBL16083759 | 0.74 | PKLR (1.00) | PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139144-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |