Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 13/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084126 | 0.79 | PKLR (0.46) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL16051041 | 0.76 | PKLR (0.58) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL14320380 | 0.74 | GRM3 (0.58) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL16084138 | 0.73 | PKLR (0.52) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL16084362 | 0.73 | PKLR (0.50) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL16049701 | 0.72 | AVPR1A (0.58) | PKLRALDH1A1LMNA | |
| SCHEMBL21976457 | 0.72 | ALDH1A1 (0.45) | PKLRCA12CA1CA2CA7 | |
| SCHEMBL21976425 | 0.71 | PKLR (0.54) | PKLRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18053843 | 0.71 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21977079 | 0.70 | PKLR (0.58) | PKLRALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139325-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |