Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052069 | 0.91 | MAPT (0.33) | OPRM1OPRK1OPRL1 | |
| SCHEMBL16927480 | 0.81 | MAPT (0.35) | OPRM1OPRK1OPRL1 | |
| SCHEMBL18065630 | 0.80 | MAPT (0.40) | — | |
| SCHEMBL7796963 | 0.79 | OPRM1 (0.39) | OPRM1OPRK1OPRL1 | |
| SCHEMBL15978065 | 0.78 | TSHR (0.38) | OPRM1OPRK1OPRL1 | |
| SCHEMBL18084817 | 0.76 | MAPT (0.35) | OPRM1OPRK1OPRL1 | |
| SCHEMBL20911099 | 0.76 | — | — | |
| SCHEMBL16084062 | 0.76 | ESR2 (0.33) | — | |
| SCHEMBL10039717 | 0.75 | GABRA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL25311167 | 0.74 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970189-B1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |
| WO-2014139325-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |