Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26187138 | 0.82 | ACHE (0.33) | ACHE | |
| Hydrochloric Acid SCHEMBL27748361 | 0.80 | ACHE (0.32) | ACHE | |
| SCHEMBL15443394 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL22299163 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL14985729 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL22299304 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL17450325 | 0.75 | ACHE (0.31) | ACHE | |
| SCHEMBL14968373 | 0.75 | ACHE (0.31) | ACHE | |
| SCHEMBL14962471 | 0.71 | PIK3CD (0.34) | — | |
| SCHEMBL357188 | 0.70 | NCF1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970323-B1 | FUROPYRIDINES AS BROMODOMAIN INHIBITORS. | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO 2) LTD (GB) | 2017-10-18 | — | — | EP | disclosed |
| US-9670221-B2 | Furopyridines as bromodomain inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
| WO-2014140077-A1 | FUROPYRIDINES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |