Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.69 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.69 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.69 |
| ▸ | ATM | Q13315 | 2/20 | 0.69 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 4/20 | 0.54 |
| ▸ | RGS12 | O14924 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703132 | 0.88 | MAPT (0.61) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL9006270 | 0.81 | KMT2A (1.00) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL24784337 | 0.78 | KMT2A (0.70) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL7712164 | 0.78 | KMT2A (0.70) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL7646448 | 0.78 | ANPEP (0.60) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL9437182 | 0.77 | USP2 (1.00) | USP2KMT2AMEN1KEAP1NFE2L2 | |
| SCHEMBL12381797 | 0.76 | NPC1 (0.42) | USP2KMT2AMEN1HTTKDM4E | |
| SCHEMBL31259865 | 0.76 | DPP4 (0.51) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL5326245 | 0.76 | DPP4 (0.51) | USP2KMT2AMEN1ATMMAPT | |
| SCHEMBL10299247 | 0.75 | KDM4E (0.57) | KMT2AMEN1CYP1B1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273274-A1 | METHODS FOR THE SELECTIVE DETECTION OF ALKYNE-PRESENTING MOLECULES AND RELATED COMPOSITIONS AND SYSTEMS | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2014-09-18 | — | — | US | disclosed |