SCHEMBL9437182

SCHEMBL9437182

CCN1C(=O)c2cccc3c(N)ccc(c23)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 8/20 1.00
KMT2A Q03164 8/20 1.00
KEAP1 Q14145 7/20 1.00
NFE2L2 Q16236 7/20 1.00
MEN1 O00255 7/20 1.00
CYP1B1 Q16678 4/20 1.00
ATM Q13315 2/20 1.00
MAPT P10636 5/20 0.78
ALDH1A1 P00352 4/20 0.78
KDM4E B2RXH2 3/20 0.78
SMN1; SMN2 Q16637 3/20 0.78
THRB P10828 2/20 0.78
NPSR1 Q6W5P4 2/20 0.78
APAF1 O14727 1/20 0.78
GAA P10253 1/20 0.78
LMNA P02545 2/20 0.68
TLR9 Q9NR96 1/20 0.68
HTT P42858 2/20 0.59
CLTC Q00610 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5309421 0.88 ALDH1A1 (1.00) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL9437193 0.88 KMT2A (0.78) USP2KMT2AKEAP1NFE2L2MEN1
Hydrochloric Acid SCHEMBL9080389 0.86 ALDH1A1 (0.97) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL3891083 0.85 KMT2A (0.74) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL16978937 0.83 USP2 (0.71) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL12023617 0.83 KMT2A (0.70) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL7646893 0.83 KMT2A (0.70) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL13964866 0.83 USP2 (0.70) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL17407730 0.82 CYP1B1 (0.69) USP2KMT2AKEAP1NFE2L2MEN1
SCHEMBL28213127 0.82 USP2 (0.68) USP2KMT2AKEAP1NFE2L2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230728-B 1,2-diketone naphthalene compounds and preparation method and application 山东大学 2016-08-24 CN claimed
CN-101941315-A Method for preparing fluorescence detection membrane containing dual-bandgap photonic crystals for fluorescence detection of explosives CHINESE ACAD INST CHEMISTRY 2011-01-12 CN claimed
US-11833784-B2 Thermoplastic film and laminated glass SEKISUI CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11801667-B2 Thermoplastic film and laminated glass SEKISUI CHEMICAL CO., LTD. (JP) 2023-10-31 US disclosed
WO-2023006909-A1 FUNCTIONALISATION OF CARBOXYMETHYLCELLULOSE THE UNIVERSITY OF MANCHESTER (GB) 2023-02-02 WO disclosed
US-20220161523-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-26 US disclosed
US-20220152992-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
US-20220154914-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
EP-3943289-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
EP-3943295-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
EP-3943288-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
CN-101941315-B Method for preparing fluorescence detection membrane containing dual-bandgap photonic crystals for fluorescence detection of explosives CHINESE ACAD INST CHEMISTRY 2012-11-28 CN disclosed
US-7910319-B2 Incubating azido-derivatized fucose analog in cell to form azido-derivatized glycoconjugate which is contacted with probe, based on copper-catalyzed cycloaddition of probe comprising alkynyl group; fucosyltransferases; microscopy ACADEMIA SINICA (TW) 2011-03-22 US disclosed
CN-101941315-A Method for preparing fluorescence detection membrane containing dual-bandgap photonic crystals for fluorescence detection of explosives CHINESE ACAD INST CHEMISTRY 2011-01-12 CN disclosed
CN-100593713-C High sensitivity photon-containing crystal explosive fluorescent checking film preparation method CHINESE ACAD INST CHEMISTRY 2010-03-10 CN disclosed
CN-101308094-A High sensitivity photon-containing crystal explosive fluorescent checking film preparation method CHINESE ACAD INST CHEMISTRY (CN) 2008-11-19 CN disclosed
US-20080241856-A1 Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo ACADEMIA SINICA (TW) 2008-10-02 US disclosed
EP-0398764-B1 An organic thin-film el device NEC CORP (JP) 1994-10-19 EP disclosed
US-5093691-A ORGANIC THIN-FILM EL DEVICE NEC CORPORATION (JP) 1992-03-03 US disclosed
EP-0398764-A2 An organic thin-film el device NEC CORPORATION (JP) 1990-11-22 EP disclosed