Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233227 | 0.82 | SLC6A3 (0.39) | SLC6A3MAOBMAOALOXL2TAAR1 | |
| SCHEMBL12134351 | 0.80 | SMN1; SMN2 (0.37) | SLC6A3MAOBMAOASLC6A4MEN1 | |
| SCHEMBL1873244 | 0.80 | SLC6A3 (0.36) | SLC6A3MAOBMAOAMEN1LMNA | |
| SCHEMBL121397 | 0.80 | EGFR (0.41) | SLC6A3MAOBMAOASLC6A4MEN1 | |
| SCHEMBL5234404 | 0.79 | SLC6A3 (0.51) | SLC6A3SLC6A4LMNASLC6A2CHRNA1 | |
| SCHEMBL2066637 | 0.79 | MAOB (0.48) | MAOBMAOATAAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6629526 | 0.78 | MAOB (0.47) | MAOBMAOATAAR1SMN1; SMN2HTR2A | |
| SCHEMBL11248214 | 0.77 | SLC6A3 (0.34) | SLC6A3MAOBMAOASLC6A4MEN1 | |
| SCHEMBL7557937 | 0.77 | EGFR (0.36) | SLC6A3MAOBMAOASLC6A4MEN1 | |
| SCHEMBL28011998 | 0.77 | EGFR (0.40) | SLC6A3MAOBMAOASLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | PROSIDION LIMITED (GB) | 2011-04-14 | — | — | US | disclosed |
| EP-1819672-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | Prosidion Limited (GB) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056815-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | IDO2, IDO1, CPT1A | SLC6A3 1281/4885MAOB 206/4885MAOA 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.