Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121397 | 0.85 | EGFR (0.41) | EGFRMAOBMAOASLC6A3MEN1 | |
| SCHEMBL28011963 | 0.81 | MAOA (0.36) | MAOBMAOASLC6A3LMNASLC6A4 | |
| SCHEMBL7557937 | 0.81 | EGFR (0.36) | EGFRMAOBMAOASLC6A3MEN1 | |
| SCHEMBL11248214 | 0.81 | SLC6A3 (0.34) | EGFRMAOBMAOASLC6A3MEN1 | |
| SCHEMBL7390254 | 0.81 | L3MBTL1 (0.45) | MAOBMAOAMEN1KMT2ASMN1; SMN2 | |
| Phosphine SCHEMBL9482786 | 0.79 | L3MBTL1 (0.44) | MAOBMAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9531677 | 0.79 | MAPK1 (0.38) | SLC6A3SMN1; SMN2SLC6A4CHRNA1CHRNG | |
| SCHEMBL13242104 | 0.79 | SLC6A4 (0.36) | MEN1LMNAPABPC1KMT2ASMN1; SMN2 | |
| SCHEMBL4053345 | 0.79 | EGFR (0.32) | EGFRMAOBMAOASLC6A3MEN1 | |
| SCHEMBL11233227 | 0.79 | SLC6A3 (0.39) | EGFRMAOBMAOASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102480956-B | Pyrido [4,3-b] indoles and methods of use | MEDIVATION TECHNOLOGIES INC | 2015-04-08 | — | — | CN | disclosed |