Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609830 | 0.92 | ELANE (0.40) | PDE10AKDM4ETSHRMAPK1ALDH1A1 | |
| SCHEMBL1609732 | 0.85 | PDE10A (0.39) | SMN1; SMN2PDE10AKDM4ETSHRMAPK1 | |
| SCHEMBL1609362 | 0.84 | PDE10A (0.40) | SMN1; SMN2PDE10AKDM4EL3MBTL1TSHR | |
| SCHEMBL1610170 | 0.83 | PDE10A (0.50) | PDE10AKDM4ETSHRMAPK1ALDH1A1 | |
| SCHEMBL1610144 | 0.83 | EGFR (0.39) | SMN1; SMN2PDE10ATSHRMAPK1ALDH1A1 | |
| SCHEMBL1609871 | 0.83 | EGFR (0.39) | SMN1; SMN2PDE10ATSHRMAPK1ALDH1A1 | |
| SCHEMBL1611523 | 0.83 | EGFR (0.39) | SMN1; SMN2PDE10ATSHRMAPK1ALDH1A1 | |
| SCHEMBL1609887 | 0.82 | PDE10A (0.40) | SMN1; SMN2PDE10AKDM4EL3MBTL1TSHR | |
| SCHEMBL1611075 | 0.82 | L3MBTL1 (0.39) | SMN1; SMN2PDE10AKDM4EL3MBTL1TSHR | |
| SCHEMBL1611073 | 0.82 | L3MBTL1 (0.39) | SMN1; SMN2PDE10AKDM4EL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SMN1; SMN2 2654/4885PDE10A 1704/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.