Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893969 | 0.87 | KMT2A (0.85) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL30914579 | 0.86 | MAPK1 (0.71) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL30267796 | 0.86 | PDE4B (0.80) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL7894613 | 0.86 | PDE4B (0.80) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL7894615 | 0.86 | MAPK1 (0.71) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL30267843 | 0.86 | PDE4B (0.80) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL5125288 | 0.83 | KMT2A (0.68) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL12846718 | 0.83 | HPGD (0.71) | KMT2AMEN1LMNAALOX15ALDH1A1 | |
| SCHEMBL30914581 | 0.82 | MAPK1 (0.65) | MAPK1KMT2AMEN1PDE4BMAPT | |
| SCHEMBL5127400 | 0.82 | KMT2A (0.67) | MAPK1KMT2AMEN1PDE4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145822-A1 | SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN | FONDAZIONE TELETHON (IT) | 2023-05-11 | — | — | US | disclosed |
| US-20140275529-A1 | SUBUNIT SELECTIVE NMDA RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | TRAYNELIS STEPHEN F (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275529-A1 | SUBUNIT SELECTIVE NMDA RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | GRIN1, GRIN2A, GRIN2B | MAPK1 1644/4885KMT2A 2345/4885MEN1 4250/4885 |
| US-20230145822-A1 | SMALL MOLECULES INDUCING THE DEGRADATION OF THE CELLULAR PRION PROTEIN | PRNP, PPIE, PPIC | MAPK1 2835/4885KMT2A 4350/4885MEN1 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.