SCHEMBL16089792

SCHEMBL16089792

c1cc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc(-c2cccc(-c3ccc4c5ccccc5c5ccccc5c4c3)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HDAC4 P56524 1/20 0.42
KMT2A Q03164 3/20 0.36
IL1R1 P14778 1/20 0.36
TSPO P30536 1/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
MAPT P10636 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
ESR1 P03372 1/20 0.35
PTPN1 P18031 2/20 0.34
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
PLA2G2A P14555 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30332621 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL12225475 1.00 L3MBTL1 (0.52) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL21388920 0.97 L3MBTL1 (0.48) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL16641560 0.95 L3MBTL1 (0.52) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL12153418 0.95 L3MBTL1 (0.57) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL16089788 0.95 L3MBTL1 (0.57) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL14849296 0.95 L3MBTL1 (0.57) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL15480159 0.94 L3MBTL1 (0.55) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL9888938 0.93 L3MBTL1 (0.59) L3MBTL1ATMKDM4EHDAC4KMT2A
SCHEMBL75854 0.93 L3MBTL1 (0.59) L3MBTL1ATMKDM4EHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10270046-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-23 US disclosed
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
EP-2866273-B1 Organic electrolumiescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-10-18 EP disclosed
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-10-27 US disclosed
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-9419225-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-08-16 US disclosed
EP-2866273-A1 Organic electrolumiescent materials and devices Universal Display Corporation (US) 2015-04-29 EP disclosed
US-20150053938-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 US disclosed
US-20140264292-A1 HOST COMPOUNDS FOR PHOSPHORESCENT OLEDS AND DEVICES THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10270046-B2 Organic electroluminescent materials and devices EML4, TYR, L1CAM L3MBTL1 656/4885ATM 3094/4885KDM4E 2646/4885
US-20160260913-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, L1CAM L3MBTL1 656/4885ATM 3094/4885KDM4E 2646/4885
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CCNL2, INTS9, SRSF9 L3MBTL1 215/4885ATM 2663/4885KDM4E 2938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.