SCHEMBL16089809

SCHEMBL16089809

c1cc(-c2ccc(-n3c4ccccc4c4ccccc43)nc2)cc(-c2ccc3c4ccccc4c4ccccc4c3c2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
HSD17B1 P14061 2/20 0.36
HSD17B2 P37059 2/20 0.36
MAPT P10636 1/20 0.35
EGLN1 Q9GZT9 2/20 0.34
MAP4K4 O95819 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHRNA7 P36544 1/20 0.32
KCNH2 Q12809 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
ALDH1A1 P00352 1/20 0.31
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16089807 1.00 CNR2 (0.37) CNR2NPC1POLBGAARAB9A
SCHEMBL16089801 0.94 NPC1 (0.39) CNR2NPC1POLBGAARAB9A
SCHEMBL16231277 0.91 L3MBTL1 (0.44) CNR2NPC1POLBGAARAB9A
SCHEMBL17692337 0.88 NPC1 (0.37) CNR2NPC1POLBGAARAB9A
SCHEMBL15034483 0.86 L3MBTL1 (0.47) NPC1POLBGAARAB9ARXFP1
SCHEMBL17692344 0.86 HPRT1 (0.39) NPC1POLBGAARAB9ARXFP1
SCHEMBL612189 0.86 KDM4E (0.43) CNR2NPC1POLBGAARAB9A
SCHEMBL19037044 0.85 EGLN1 (0.38) CNR2NPC1RAB9AHSD17B1HSD17B2
SCHEMBL16089836 0.84 NPC1 (0.35) NPC1POLBGAARAB9ARXFP1
SCHEMBL16089835 0.82 PDE4A (0.39) MAPTMAP4K4KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
US-9831437-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-28 US disclosed
EP-2866273-B1 Organic electrolumiescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-10-18 EP disclosed
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-10-27 US disclosed
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-10-27 US disclosed
US-9419225-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-08-16 US disclosed
US-9419225-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-08-16 US disclosed
EP-2866273-A1 Organic electrolumiescent materials and devices Universal Display Corporation (US) 2015-04-29 EP disclosed
US-20150053938-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 US disclosed
US-20150053938-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 US disclosed
US-20140264292-A1 HOST COMPOUNDS FOR PHOSPHORESCENT OLEDS AND DEVICES THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2014-09-18 US disclosed
US-20140264292-A1 HOST COMPOUNDS FOR PHOSPHORESCENT OLEDS AND DEVICES THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160315269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CCNL2, INTS9, SRSF9 CNR2 2106/4885NPC1 3837/4885POLB 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.