SCHEMBL612189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4546808	0.91	L3MBTL1 (0.50)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL16089801	0.88	NPC1 (0.39)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL17952785	0.87	KDM4E (0.42)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL17952774	0.87	KDM4E (0.42)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL16089807	0.86	CNR2 (0.37)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL16089809	0.86	CNR2 (0.37)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL17692337	0.86	NPC1 (0.37)	KDM4EATML3MBTL1ALDH1A1CNR2
	SCHEMBL12036267	0.85	KDM4E (0.39)	KDM4EATML3MBTL1ALDH1A1CHRNA7
	SCHEMBL22940854	0.85	NPC1 (0.39)	KDM4EATML3MBTL1ALDH1A1CYP1A2
	SCHEMBL22068512	0.84	KDM4E (0.40)	KDM4EATML3MBTL1ALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.