Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 15/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107472 | 0.86 | PYGL (0.51) | PYGLIDO1 | |
| SCHEMBL13271729 | 0.82 | PYGL (0.48) | PYGLIDO1 | |
| SCHEMBL1608132 | 0.80 | PYGL (0.57) | PYGLNHERF1HRH4HRH3 | |
| SCHEMBL12738418 | 0.79 | PYGL (0.60) | PYGLIDO1NHERF1HRH4HRH3 | |
| SCHEMBL1608870 | 0.79 | PYGL (0.60) | PYGLIDO1NHERF1HRH4HRH3 | |
| SCHEMBL1608140 | 0.79 | PYGL (0.59) | PYGLNHERF1HRH4HRH3 | |
| SCHEMBL5891883 | 0.77 | PYGL (0.67) | PYGLNHERF1HRH4HRH3 | |
| SCHEMBL23014252 | 0.77 | TSHR (0.64) | — | |
| SCHEMBL1609640 | 0.77 | FLT3 (0.60) | PYGLHRH4HRH3 | |
| SCHEMBL6162686 | 0.76 | PYGL (0.65) | PYGLNHERF1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | PROSIDION LIMITED (GB) | 2011-04-14 | — | — | US | disclosed |
| US-20110086885-A1 | Indole-2-carboxylic acid amides | PROSIDION LIMITED (GB) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086885-A1 | Indole-2-carboxylic acid amides | IDO2, IDO1, CPT1A | PYGL 152/4885IDO1 2/4885NHERF1 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.