Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 17/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608813 | 0.88 | PDE10A (0.38) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1610037 | 0.86 | ALDH1A1 (0.44) | PDE10ANAPEPLD | |
| SCHEMBL1609980 | 0.84 | CHRM3 (0.43) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609435 | 0.82 | PDE4B (0.45) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12713104 | 0.82 | PDE4B (0.43) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12713234 | 0.82 | PDE4A (0.39) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1610143 | 0.82 | KDM4E (0.38) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609602 | 0.82 | PDE4B (0.41) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12712701 | 0.81 | CHRM3 (0.41) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609694 | 0.81 | SMN1; SMN2 (0.41) | CHRM3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | CHRM3 2705/4885PDE4A 1115/4885PDE4B 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.