Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713240 | 0.90 | CHRM3 (0.39) | SMN1; SMN2ALDH1A1HSD17B10PDE4ARAB9A | |
| SCHEMBL1610224 | 0.88 | SLC6A3 (0.40) | SMN1; SMN2ALDH1A1HSD17B10PDE4AMEN1 | |
| SCHEMBL1609455 | 0.87 | KMT2A (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1609979 | 0.83 | PDE4B (0.42) | SMN1; SMN2ALDH1A1PDE4ARAB9ACHRM3 | |
| SCHEMBL1610432 | 0.82 | TSHR (0.40) | SMN1; SMN2ALDH1A1HSD17B10PDE4AMEN1 | |
| SCHEMBL1609421 | 0.82 | PDE10A (0.43) | SMN1; SMN2ALDH1A1HSD17B10PDE4AMEN1 | |
| SCHEMBL1609728 | 0.82 | PDE10A (0.42) | ALDH1A1PDE4AMEN1KMT2ACHRM3 | |
| SCHEMBL1609435 | 0.82 | PDE4B (0.45) | SMN1; SMN2ALDH1A1PDE4AMEN1KMT2A | |
| SCHEMBL1608874 | 0.82 | SLC6A3 (0.39) | SMN1; SMN2ALDH1A1HSD17B10PDE4AMEN1 | |
| SCHEMBL1609980 | 0.82 | CHRM3 (0.43) | SMN1; SMN2ALDH1A1PDE4AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SMN1; SMN2 2654/4885ALDH1A1 1562/4885HSD17B10 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.