Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120609 | 0.88 | RAB9A (0.54) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1609680 | 0.81 | MAPT (0.47) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1609024 | 0.81 | MAPT (0.57) | SMN1; SMN2RAB9ANPC1NPSR1F2 | |
| SCHEMBL1610594 | 0.80 | MAPT (0.55) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1611172 | 0.79 | RAB9A (0.51) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1610482 | 0.78 | PTGS2 (0.47) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1610317 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMAPTHSD17B10REN | |
| SCHEMBL12713301 | 0.77 | APP (0.43) | SMN1; SMN2RAB9ANPC1NPSR1F2 | |
| SCHEMBL1610660 | 0.77 | SOS1 (0.44) | SMN1; SMN2TP53RAB9ANPC1NPSR1 | |
| SCHEMBL1610095 | 0.77 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1NPSR1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SMN1; SMN2 2654/4885TP53 731/4885RAB9A 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.