SCHEMBL1609319

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3815519	0.87	ALDH1A1 (0.33)	ALDH1A1PRKD3PRKCGPRKCBPRKCA
	SCHEMBL29186006	0.84	GRIN2D (0.43)	ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL1609981	0.80	GAA (0.41)	ALDH1A1MEN1KMT2AMAPTKDM4E
	SCHEMBL15440586	0.78	ALDH1A1 (0.46)	ALDH1A1MAPTGPR35S100A4HPGD
	SCHEMBL22543060	0.76	BCL2 (0.50)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL31167470	0.76	ALDH1A1 (0.43)	ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
	SCHEMBL7435273	0.74	BCL2 (0.63)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL343597	0.73	BCL2 (0.39)	ALDH1A1MEN1KMT2AMAPTHPGD
	SCHEMBL21291914	0.72	ALDH1A1 (0.50)	ALDH1A1MEN1KMT2AMAPTGPR35
	SCHEMBL11654706	0.71	ALDH1A1 (0.46)	ALDH1A1MEN1KMT2AMAPTS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.