Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541230 | 1.00 | FOLH1 (0.38) | FOLH1TDP1ATMPOLBKMT2A | |
| SCHEMBL16151455 | 0.92 | FOLH1 (0.35) | FOLH1TDP1POLBKMT2AHDAC8 | |
| SCHEMBL18161564 | 0.86 | TDP1 (0.39) | FOLH1TDP1ATMPOLBKMT2A | |
| SCHEMBL15510867 | 0.86 | TDP1 (0.39) | FOLH1TDP1ATMPOLBKMT2A | |
| SCHEMBL15510866 | 0.86 | TDP1 (0.39) | FOLH1TDP1ATMPOLBKMT2A | |
| SCHEMBL24630327 | 0.84 | KMT2A (0.38) | TDP1ATMPOLBKMT2AMAPT | |
| SCHEMBL18145473 | 0.83 | KMT2A (0.41) | TDP1POLBKMT2AL3MBTL1HDAC8 | |
| SCHEMBL14729303 | 0.83 | KMT2A (0.41) | TDP1POLBKMT2AL3MBTL1HDAC8 | |
| SCHEMBL18161562 | 0.83 | KMT2A (0.41) | TDP1POLBKMT2AL3MBTL1HDAC8 | |
| SCHEMBL15495587 | 0.83 | TDP1 (0.37) | FOLH1TDP1ATMPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159611-A1 | SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) | YALE UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
| EP-2968552-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | The California Institute for Biomedical Research (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153164-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159611-A1 | SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) | CD47, CD4, CD2 | FOLH1 148/4885TDP1 4315/4885ATM 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.