SCHEMBL16094017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5783703	0.94	ALDH1A1 (0.55)	ALDH1A1HPGDKDM4EAKR1C3AKR1C2
	SCHEMBL27989931	0.86	ALDH1A1 (0.57)	ALDH1A1HPGDKDM4EHTTCLCN2
	SCHEMBL16117941	0.85	ALDH1A1 (0.54)	ALDH1A1HPGDKDM4ELCKFYN
	SCHEMBL5783619	0.81	ALDH1A1 (0.51)	ALDH1A1HPGDKDM4ETUBB4ATUBB
	SCHEMBL27838174	0.81	DHODH (0.53)	ALDH1A1HPGDKDM4EAKR1C3AKR1C2
	SCHEMBL16099343	0.81	ALDH1A1 (0.50)	ALDH1A1HPGDKDM4EHTTNPC1
	SCHEMBL22089318	0.80	ALDH1A1 (0.57)	ALDH1A1HPGDKDM4EAKR1C2HTT
	SCHEMBL16102950	0.79	PRKAB2 (0.51)	ALDH1A1HPGDKDM4ETUBB4ATUBB
	SCHEMBL3387534	0.78	ALDH1A1 (0.56)	ALDH1A1HPGDKDM4EHTTCLCN2
	SCHEMBL5804072	0.78	ALDH1A1 (0.48)	ALDH1A1HPGDKDM4EAKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.