Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521941 | 0.90 | HTT (0.52) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL19477840 | 0.88 | HTT (0.57) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17501963 | 0.86 | MEN1 (0.49) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5050709 | 0.85 | HTT (0.57) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL328476 | 0.85 | HTT (0.57) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7514786 | 0.84 | HTT (0.73) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL127662 | 0.83 | HTT (0.82) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17521942 | 0.82 | MEN1 (0.46) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22844723 | 0.82 | HTT (0.53) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| Hydrochloric Acid SCHEMBL7400993 | 0.82 | HTT (0.79) | HTTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-18 | — | — | US | disclosed |
| US-20160038615-A1 | SACCHARIDE CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-11 | — | — | US | disclosed |
| WO-2014152718-A1 | SACCHARIDE CONJUGATES | ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014152718-A1 | SACCHARIDE CONJUGATES | ARIZONA BOARD OF REGENTS, FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | FUT5, FUT6, B3GNT2 | HTT 3197/4885MEN1 3709/4885KMT2A 1202/4885 |
| US-20160038615-A1 | SACCHARIDE CONJUGATES | BLM, DCLRE1A, MAN1B1 | HTT 1879/4885MEN1 110/4885KMT2A 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.