Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | AR | P10275 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.71 |
| ▸ | IL6 | P05231 | 1/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.71 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.71 |
| ▸ | GLUL | P15104 | 1/20 | 0.71 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634790 | 0.95 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL136773 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL21152533 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL13130881 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL20451347 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL24622433 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL7512 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL21152848 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL26490459 | 0.93 | PGR (0.78) | PGRHIF1ANR3C1HSD17B10AR | |
| Prednisolone Phosphoric Acid SCHEMBL5483617 | 0.93 | PGR (0.77) | PGRHIF1ANR3C1HSD17B10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2967984-A1 | IMPLANTS WITH CONTROLLED DRUG DELIVERY FEATURES AND METHODS OF USING SAME | Dose Medical Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150292-A1 | IMPLANTS WITH CONTROLLED DRUG DELIVERY FEATURES AND METHODS OF USING SAME | DOSE MEDICAL CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |