Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.69 |
| ▸ | KDM5A | P29375 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102665 | 0.86 | KDM4C (0.68) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095130 | 0.86 | KDM4C (0.69) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095526 | 0.86 | KDM4C (0.69) | KDM4CKDM2B | |
| SCHEMBL16033749 | 0.82 | KDM4C (1.00) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095268 | 0.80 | KDM4C (0.45) | KDM4CCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL16095141 | 0.76 | KDM4C (0.61) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095042 | 0.72 | KDM4C (0.67) | KDM4CKDM5AKDM2B | |
| SCHEMBL16033615 | 0.71 | KDM4C (1.00) | KDM4CKDM5AKDM2B | |
| SCHEMBL16095534 | 0.69 | KDM4C (0.62) | KDM4CKDM2B | |
| SCHEMBL17693323 | 0.68 | KDM4C (0.74) | KDM4CKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |