Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102461 | 0.85 | KDM4C (0.42) | KDM4CMAPK14GRIN1GRIN2B | |
| SCHEMBL16094945 | 0.84 | KDM4C (0.51) | KDM4CMAPK14 | |
| SCHEMBL16095137 | 0.80 | KDM4C (0.69) | KDM4CCDK2CDK9CCNT1CCNA2 | |
| SCHEMBL16095479 | 0.80 | KDM4C (0.65) | KDM4CMAPK14 | |
| SCHEMBL16034902 | 0.79 | KDM4C (0.66) | KDM4CCDK2CDK9CCNT1CCNA2 | |
| SCHEMBL17604614 | 0.76 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL16095270 | 0.73 | KDM4C (0.44) | KDM4CCDK2CDK9CCNT1CCNA2 | |
| SCHEMBL17604576 | 0.72 | KDM4C (0.47) | KDM4CMAPK14GRIN2B | |
| SCHEMBL17604573 | 0.71 | PKM (0.41) | KDM4CMAPK14L3MBTL1 | |
| SCHEMBL16095596 | 0.71 | KDM4C (0.65) | KDM4CCDK9CCNT1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |