Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095164 | 0.90 | HCRTR1 (0.40) | PHF8HCRTR1HCRTR2KDM4CNPY5R | |
| SCHEMBL16095874 | 0.83 | KDM2B (0.39) | KDM4CNPY5RKCNH2KDM2BCYP2D6 | |
| SCHEMBL16095079 | 0.81 | ADORA2A (0.39) | PHF8KDM4CNPY5RMAPK1 | |
| SCHEMBL16095102 | 0.79 | PHF8 (0.41) | PHF8KDM4CNPY5R | |
| SCHEMBL16094315 | 0.78 | KDM4C (0.65) | PHF8KDM4CKDM2B | |
| SCHEMBL16095234 | 0.77 | PHF8 (0.40) | PHF8KDM4CKDM2B | |
| SCHEMBL16095813 | 0.77 | PHF8 (0.39) | PHF8KDM4CNPY5RMAPK1 | |
| SCHEMBL16095040 | 0.77 | NPY5R (0.36) | HCRTR1HCRTR2NPY5RKCNH2 | |
| SCHEMBL16095150 | 0.76 | PHF8 (0.41) | PHF8HCRTR1HCRTR2KDM4CNPY5R | |
| SCHEMBL16033687 | 0.75 | KDM4C (0.61) | PHF8HCRTR1HCRTR2KDM4CKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |