Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095813 | 0.86 | PHF8 (0.39) | PHF8KDM4CP2RX7NPY5R | |
| SCHEMBL16095234 | 0.82 | PHF8 (0.40) | PHF8KDM5AKDM4CCTSKCRHR1 | |
| SCHEMBL16095079 | 0.82 | ADORA2A (0.39) | PHF8KDM4CNPY5R | |
| SCHEMBL16095164 | 0.81 | HCRTR1 (0.40) | PHF8KDM4CNPY5R | |
| SCHEMBL17604542 | 0.79 | PHF8 (0.39) | PHF8KDM4CP2RX7TAAR1 | |
| SCHEMBL16095263 | 0.79 | PHF8 (0.39) | PHF8KDM4CNPY5R | |
| SCHEMBL16095001 | 0.79 | TAAR1 (0.44) | KDM4CTAAR1NPY5R | |
| SCHEMBL16095072 | 0.78 | KDM4C (0.65) | PHF8KDM5AKDM4C | |
| SCHEMBL16095540 | 0.77 | GRM5 (0.43) | — | |
| SCHEMBL16095040 | 0.76 | NPY5R (0.36) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |