Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095164 | 0.85 | HCRTR1 (0.40) | KDM2BKDM4CALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16095263 | 0.83 | PHF8 (0.39) | KDM2BKDM4CALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16095079 | 0.80 | ADORA2A (0.39) | KDM4CMAPK1NPY5RTSHR | |
| SCHEMBL16095150 | 0.80 | PHF8 (0.41) | KDM2BKDM4CALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16095813 | 0.76 | PHF8 (0.39) | KDM4CMAPK1NPY5RTSHR | |
| SCHEMBL16034914 | 0.76 | KDM4C (0.62) | KDM2BKDM4CKCNH2 | |
| SCHEMBL16095066 | 0.72 | PHF8 (0.41) | KDM4CMAPK1TSHR | |
| SCHEMBL16095001 | 0.72 | TAAR1 (0.44) | KDM4CMEN1KMT2ANPY5RKCNH2 | |
| SCHEMBL16095102 | 0.72 | PHF8 (0.41) | KDM4CNPY5R | |
| SCHEMBL16094923 | 0.72 | PHF8 (0.43) | KDM2BKDM4CMAPK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |