Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499187 | 0.87 | MEN1 (0.33) | MEN1KMT2ATAAR1CTHGAA | |
| SCHEMBL16097757 | 0.85 | MAOA (0.44) | MEN1KMT2ATAAR1CTHLMNA | |
| SCHEMBL16097678 | 0.82 | MEN1 (0.34) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL16098722 | 0.82 | MEN1 (0.34) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL16097842 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2ATAAR1GAALMNA | |
| SCHEMBL16099271 | 0.79 | MEN1 (0.38) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL16104945 | 0.79 | MEN1 (0.34) | MEN1KMT2ATAAR1DYRK3CLK1 | |
| SCHEMBL16096005 | 0.78 | MEN1 (0.43) | MEN1KMT2ATAAR1GAADYRK3 | |
| SCHEMBL16097741 | 0.77 | TAAR1 (0.39) | MEN1KMT2ATAAR1GAADYRK3 | |
| SCHEMBL16097183 | 0.77 | MEN1 (0.36) | MEN1KMT2ATAAR1DYRK3CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |